TANGRAM¶
Tangram is a Python package, written in PyTorch and based on scanpy , for mapping single-cell (or single-nucleus) gene expression data onto spatial gene expression data. The single-cell dataset and the spatial dataset should be collected from the same anatomical region/tissue type, ideally from a biological replicate, and need to share a set of genes. Tangram aligns the single-cell data in space by fitting gene expression on the shared genes. The best way to familiarize yourself with Tangram is to check out our tutorials.
Tangram News¶
Citing Tangram¶
Tangram has been released in the following publication
Biancalani* T., Scalia* G. et al. - _Deep learning and alignment of spatially-resolved whole transcriptomes of single cells in the mouse brain with Tangram biorXiv 10.1101/2020.08.29.272831 (2020)